Means "Saint James", derived from Spanish santo "saint" combined with Yago, an old Spanish form of JAMES, the patron saint of Spain. Cities in Chile and Spain bear this name.
Famous People: Santiago Calatravawiki (Architect, 1951, Spain), Santiago Ramón y Cajalwiki (Physician, 1852, Spain), Santiago Bernabéu Yestewiki (Soccer Player, 1895, Spain), Santiago Cañizareswiki (Soccer Player, 1969, Spain), Santiago Carrillowiki (Politician, 1915, Spain)